Natural product-based Anti-ageing therapy: Kaempherol, found in leeks, apples, and onions, increases the expression of immortality gene telomerase via down regulation of its target genes

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Citation:Boominathan,Natural product-based Anti-ageing therapy: Kaempherol, found in leeks, apples, and onions,increases the expression of immortality gene telomerase via down regulation of its target genes, 13/June/2015, 11.36 pm,Genome-2-Bio-MedicineDiscovery center(GBMD),http://genomediscovery.org

Significance:It has been shown earlier that transgenic expression of telomerase increases the longevity of mice.This study suggests, for the first time, that Kaempherol,by decreasing the expression of its target gene,it may increasethe expression of (1) immortality gene telomerase; and (2) the longevity-promoting gene Sirtuin-1. Thereby, it may increase the life-span of an individual.Thus,pharmacological formulationsencompassing“Kaempherolor its analogues” can be used to decrease ageing and increase the life-span of an individual.

Undisclosed information:How Kaempherolincreasesthe expression of immortality gene telomerase

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