Category - CANCER/CANCER STEM CELLS

CANCER/CANCER STEM CELLS

Natural product therapy for KRAS-mutant lung cancer: Thymoquinone, the most abundant component in Black Cumin – Nigella sativa, decreases the expression of XPO1, increases the level of NFKBIA, inhibits NFKB transcriptional activity and suppresses the progression of KRAS-mutant lung cancer via up regulation of its target gene

CANCER/CANCER STEM CELLS

Therapeutic insights into PD-1 pathway blockade for Human cancer therapy: Olea europaea leaf extract (OLE) inhibits the expression of co-inhibitory receptor PD-1 on Antigen- Specific T-cells, increases the production of cytokines by tumor-infiltrating lymphocytes (TIL), and draining lymph nodes and augments anti-tumor activity via down regulation of its target gene

CANCER/CANCER STEM CELLS

Natural product therapy targeting aberrant Lipid synthesis in Human cancers: 8-hydrocalamenene, derived from Reynoutria elliptica, suppresses the expression of the principal enzyme in lipid synthesis, ACLY, inhibits aberrant lipid production in cancer cells and tumor progression via up regulation of its target gene

CANCER/CANCER STEM CELLS RECENT IDEAS

Natural product therapy targeting aberrant Lipid synthesis in Human cancers: Litchi (Litchi chinensis) flower extract suppresses the expression of the principal enzyme in lipid synthesis, ACLY, inhibits aberrant lipid production in cancer cells and tumor progression via up regulation of its target gene

CANCER/CANCER STEM CELLS

Natural product Anti-telomerase cancer therapy: Honokiol, a bioactive constituent of Magnolia-grandiflora/dealbata/obovata/officinalis, suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down regulation of its target gene

CANCER/CANCER STEM CELLS

Natural product therapy for KRAS-mutant lung cancer: Thymoquinone, the most abundant component in Black Cumin – Nigella sativa, decreases the expression of XPO1, increases the level of NFKBIA, inhibits NFKB transcriptional activity and suppresses the progression of KRAS-mutant lung cancer via up regulation of its target gene

CANCER/CANCER STEM CELLS

Therapeutic insights into PD-1 pathway blockade for Human cancer therapy: Agaricus blazei Murill (AbM) inhibits the expression of co-inhibitory receptor PD-1 on Antigen- Specific T-cells, increases the production of cytokines by tumor-infiltrating lymphocytes (TIL), and draining lymph nodes and augments anti-tumor activity via down-regulation of its target gene